Advantage II for Dogs

$50.98 - $66.98
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Product Description


Advantage II for Dogs 

by Bayer Animal Health

NEW Advantage II with IGR is the best - by far - of any insect control for your pets!

Advantage II is a fast topical flea control for dogs. It kills 98-100% of adult fleas within 12 hours of application. And it kills reinfesting fleas within two hours. One convenient application of Advantage keeps working for up to 30 days a month.

Key Benefits

  • Stops biting in 3–5 minutes.
  • Kills through contact –– Fleas don't have to bite to die.
  • Kills adult fleas fast — before they lay eggs.
  • Kills flea larvae — before they develop into biting fleas.
  • Breaks the flea life cycle at multiple stages.
  • Gentle enough puppies as young as 7 weeks and weighing at least 3 lbs.
  • 100% client satisfaction guaranteed.
  • Waterproof*

*Use of soap-free shampoo when bathing is recommended.

Advantage Flea Control is a liquid "spot on" topical insecticide.

Advantage Flea Control comes in a tube that you "snip" open and 'spot on' between your pet's shoulder blades once a month. 

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How it Works

Our own testing and many of our customers have found Advantage II and Advantix II to be much more effective than Frontline and Frontline Plus. We have found that Advantage and Advantix are not only more effective, they also remain effective longer than the other brands.

We will continue to stock both the Advantage II and Advantix II and the Frontline Topspot /Frontline Plus lines, however, we strongly recommend Advantage II and Advantix II over all other flea and tick controls.

Advantage II takes superior flea control to the next level with the addition of the insect growth regulator (IGR) pyriproxyfen. Advantage II actively targets the ENTIRE flea life cycle for effective treatment of existing fleas and prevention of flea infestation.

Advantage II still contains the proven active ingredient, imidacloprid, found in Advantage, which kills 98-100% of adult fleas within 12 hours, stops fleas from biting in 3-5 minutes, and kills re-infesting fleas within 2 hours. The result is fast-acting relief from biting adults whether your dog has fleas or picks up fleas from another animal.

The addition of the insect growth regulator (IGR) pyriproxyfen means Advantage II inhibits the development of flea eggs and larvae to break the flea life cycle, so there is no development into biting, breeding adults. Advantage II is a non-prescription topical flea control treatment specializing in fast, convenient and economical flea control. Also an effective treatment for chewing lice on dogs.

Advantage II remains effective following a shampoo treatment, swimming, or after exposure to rain or sunlight. No-odor, easy-squeeze tube makes it easy to apply. One tube can be effective for up to one month. Each package contains pre-measured, childproof, easy-to-use squeeze tubes. For dogs only: 7 weeks or older.

Do not use on cats.


It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

How to Open

Be sure the tube is at bottom of the pouch.
Using scissors, cut the pouch across the top and remove the tube.

How to Apply

Use only on dogs. Do not use on other animals.
Remove one applicator tube from the package.
Hold applicator tube in an upright position. Pull the cap off tube.
Turn the cap around and place the other end of cap back on the tube.
Twist cap to break seal, then remove the cap from tube.


For Dogs 10 lbs and under & 11-20 lbs: The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your dog's eyes or mouth.

For Dogs 21-55 lbs & Over 55 lbs: The dog should be standing for easy application. The entire contents of the Advantage II tube should be applied evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog.

Do not get this product in your pet's eyes or mouth.
Discard empty tube as described in Storage and Disposal.
In case of a severe flea infestation, retreatment may be necessary earlier than four weeks.
Do not retreat more often than once every seven days.
After flea control is attained, return to a monthly retreatment schedule.

1 Review Hide Reviews Show Reviews

  • 5
    Flea and tick...

    Posted by James Leslie on Dec 6th 2022

    I've been using Advantage on my dog for the last year and she has not been scratching and no fleas are showing up when she gets her bath.